![Prostate specific serum 2](https://kumkoniak.com/36.jpg)
![prostate specific serum 2 prostate specific serum 2](https://ai2-s2-public.s3.amazonaws.com/figures/2017-08-08/d64daf5648bdd92017b9ddc3bccdcd0966ed8503/6-Table2-1.png)
Up to 20% of men with negative biopsy results have subsequently been found to have cancer.īased on free PSA:total PSA ratio: the percent probability of finding prostate cancer on a needle biopsy by age in years:ġ. However, even a negative result of prostate biopsy does not rule-out prostate cancer.
![prostate specific serum 2 prostate specific serum 2](https://www.auanet.org/images/Education/clinical-guidance/Prostate-Specific-Antigen-Figure-2.jpg)
Therefore, some urologists recommend using the free PSA:total ratio to help select which men should undergo biopsy. The total PSA range of 4.0 to 10.0 ng/mL has been described as a diagnostic "gray zone," in which the free PSA:total PSA ratio helps to determine the relative risk of prostate cancer (see table).
![prostate specific serum 2 prostate specific serum 2](https://img.medscapestatic.com/pi/meds/ckb/07/23507tn.jpg)
When total PSA concentration is above 10.0 ng/mL, the probability of cancer is high and prostate biopsy is generally recommended. When total prostate-specific antigen (PSA) concentration is below 2.0 ng/mL, the probability of prostate cancer in asymptomatic men is low, further testing and free PSA may provide little additional information.
![Prostate specific serum 2](https://kumkoniak.com/36.jpg)